This extra binding energy is made available as a result of the mechanism of neutron pairing effects.
2.
The oldest known written recipe for something similar to pease pudding involves saffron, nutmeg and a little cinnamon in the blending process; modern recipes sometimes beat in an egg at this point to act as an extra binding agent.
3.
There are several recent reviews of the structure-activity relationships of 5HT2A agonists that I could dig out, and a lot of the modelling work being done on the 5HT2A receptor these days is using NBOMe compounds because of the extra binding motif.
4.
The SEMF gives a good approximation for atomic masses and several other effects, but does not explain the appearance of magic numbers of protons and neutrons, and the extra binding-energy and measure of stability that are associated with these numbers of nucleons.
5.
The size and complexity of a bindery shop varies with job types, for example, from one of a kind custom jobs, to repair / restoration work, to library rebinding, to preservation binding, to small edition binding, to extra binding, and finally to large run publisher's binding.